Sealed Sources

Sealed source fabrication facilities RAPPCOF at Rawatbhata, HIRUP & Radiological Laboratories at Trombay and IFRT at Vashi are engaged in meeting the ever increasing demand of sealed sources in the country. These sources are manufactured using sophisticated equipment under stringent quality control to meet the prescribed standards by leak and contamination test Performance of these sources is ensured under conditions of normal use as well as anticipated accidental conditions. The sources conform to various national and international standard i.e. AERB standard SS-3 (2001) with a typical classification designation of E 65535 and Special Form Radioactive Material.

Cobalt teletherapy sources (CTS)

Cobalt Teletherapy sources for radiation treatment of cancer are also fabricated and supplied to various users as per the requirements.These sources are manufactured using sophisticated equipment under stringent quality control to meet the prescribed standards by leak and contamination test. Performance of these sources is ensured under conditions of normal use as well as anticipated accidental conditions Sources for all types of Cobalt Teletherapy Machines including Bhabhatron and imported Theratron or any other machines in the country are fabricated as per the standard with classification designation as E65535 and also as Special Form Radioactive Material. Cobalt Teletherapy Sources are supplied under code CTS in the output range of 100-250 RMM depending on the requirement of the users. Transportation and installation is the responsibility of agents of the unit. More information on Bhabhatron-II is available on the website of Bhabha Atomic Research Centre (BARC).

 
Irradiator sources

Sources for various types of irradiator sources for use in the country and abroad are fabricated as per the standard with typical classification designation as E65535 or E64535 with bend test 5 and also as Special Form Radioactive Material.

With several radiation processing plants commissioned in the private sector after signing up MoU with BRIT, the requirement for industrial irradiator sources has rapidly increased. For example BRIT supplied 882 kCi of Cobalt-60 industrial irradiator sources to NIPRO in a single order. The list of radiation processing plants commissioned in private sector and the MoUs signed are available at this website. (RPP in Private Sector)

  •   For Dry Type Industrial Irradiators (ISOMED)
  •   For Wet Type Industrial Irradiators (RPP Vashi and several radiation processing plants in private sector)
  •   For small research irradiators and gamma chambers (GC 5000 & BI 2000)
  •   Custom built sources as per request
Radiography sources

BRIT fabricates sources for various indigenous ROLI and other imported radiographic exposure devices incorporating Ir-192, Co-60 as per standard with classification designation as E65535 and also as Special Form Radioactive Material. Gamma-emitting industrial radiography sources are used to "X-Ray" metal that would be too thick for conventional x-rays. They are also used in confined areas that are too small for a portable x-ray machine.
A source typically consists of Ir-192 or Co-60 that is housed in a small metal capsule at one end of a short flexible cable called a "pig tail". At the other end of the pig tail is a connector that is used to attach the source to a long "crank-out" cable. The crank-out cable allows the radiographer to operate the source at a safe distance.

Nucleonic Gauge

Nucleonic gauges and many control systems require sealed radiation sources fabricated as per the customer requirements. BRIT fabricates and supplies custom made radiation sources incorporating Co-60 as per standard with classification designation as E65535 for these applications.

A nucleonic gauge consists of a suitable radiation source arranged in a fixed geometrical relationship with one or more radiation detectors. Nucleonic Gauges mostly use radioactive sources, normally of milli-curie (mCi) activity. The radiation shields, useful beam controls and other components form an integral part of the device.Nucleonic Gauges are also known as Ionizing Radiation Gauging Device (IRGDs). It is used for determination of thickness of steel plate, paper, film; measurement of density and composition of materials; level measurement; control of process material in closed containers i.e. mould level measurement; moisture content in blast furnace; analysis of ores and minerals etc.

 
Brachytherapy sources

In brachytherapy, the radiation dose is applied to tumor by sealed sources. The sources are implanted or placed for a certain period of time to the tumor tissue itself or in its close vicinity.

BRIT has designed and developed Ir-192 based brachytherapy unit, Karknidon which is likely to be available in the market very soon. One such unit has been provided to Tata Memorial Centre for trial runs.

Ruthenium-106 Plaque Therapeutic

Ru-106 plaques brachytherapy cures eye cancers, salvage visions and saves life.

Plaque Brachytherapy in Eye Cancer Treatment Applications :

Plaque brachytherapy is a well proven modality for treatment of various eye cancers like uveal melanoma, retinoblastoma and choroidal melanomas.

Among the various radionuclides that can be used for plaque brachytherapy, Ru-106 plaques have gained wide popularity owing to a combination of unique radiochemical characteristics and excellent performance in terms of vision salvage. Further, the plaque needs no assembly and can be used as provided.

Ru-106 based brachytherapy delivers selective radiation dose emitted from its daughter Rh-106 (E = 3.54 MeV) as it decays to stable Pt-106, which minimizes damage to healthy tissues of the eye.

Importantly, the long half life of the parent radioisotope (Ru-106) makes the sources useful for treatment of multiple patients over a period of one year.

Offerings :

The Department of Atomic Energy (DAE) has dedicated two plaques for affordable eye cancer treatment.

Product code Descriptions Diameter Activity range
RUM1 Ru-106 Round (A) Plaque 15.8 mm 15-37 MBq
RUM2 Ru-106 Notched (N) Plaque 21.0 mm 20-50 MBq

Plaques and accessories :

Each plaque comes with :

  • One silver dummy plaque
  • Certificate
  • Dosimetry report
  • Dose distribution profile
 

Ru-106 Round (A) Plaque :

Round plaque is extremely useful for the treatment of retinoblastoma, uveal and choroidal melonomas. The plaque is available with wide a range of activities which helps ophthalmologists select a suitable plaque depending upon the treatment required. Almost 40% of eye cancer patients can be treated using this plaque design.

Technical specification of the plaque is as follows :

  • Material : Silver (99.9%)
  • Outer diameter : 15.8 mm
  • Active core diameter : 13.3 mm
  • Spherical radius : 12 mm
  • Total thickness : 1 mm
  • Source strength : 15-37 MBq
  • Useful life : 1 year
  • Maximum uses : 50 times
  • Source classification : : C 43312

Dosimetry profile :

The dosimetry profile of each plaque is determined using a radiochromic film in a tissue equivalent phantom. The absorbed dose to water at different distances (in axial direction) from the plaque is measured. A typical dosimetry profile of a plaque is represented below for reference.

Additionally, dose distribution data both vertical and horizontal direction is generated by a computer simulation programme. The computed dose distribution not only assists doctors for planning the treatment, but also helps in estimating dose distribution to other parts of the eye.

Ru-106 Notched (N) Plaque :

The notched plaque is developed for treatment of eye cancers located near the optical nerve. Unique design of the plaque facilitates selective dose delivery to the tumor while sparing the optical nerve, which is the most important part of the eye. The plaque is available with a wide range of activities, with low dose rates chosen smaller tumors, typically prevalent in children. The high active sources are useful for treatment of larger tumors upto 6 mm in height. High active plaques can be used for surface tumor treatment applications even beyond one year. Almost 50% of eye cancer patients can be treated with this plaque.

  • Material : Silver (99.9%)
  • Outer diameter : 21.0 mm
  • Active core diameter : 18.5 mm
  • Spherical radius : 12 mm
  • Total thickness : 1 mm
  • Source strength : 20-50 MBq
  • Useful life : 1 year
  • Maximum uses : 50 times
  • Source classification : : C 43312

Highlights :

  • Fission Ru-106 has been recovered in radiochemically pure form and used in the plaque preparation.
  • Plaque manufacturing is done under stringent regulatory guidelines.
  • Quality assurance tests for each plaque are done as per AERB SS3 guidelines endorsed by third party examination.
  • The plaque can be sterilized by autoclave method after every use. Plaque integrity after 75 times of sterilization (autoclave conditions:121oC, 15 psi, 30 min) is ensured.
  • Indigenous development of the plaque ensures affordable eye cancer treatment.

 

Ordering process :

 

Customer review :

Click here for Customer Review

 

For order related assistance, contact :

rphp@britatom.gov.in

(022) 27887254

For product related query, contact :

Dr. C.P. Kaushik

adnrg@barc.gov.in

(022) 25595528

Contact :

Jacob Sebastian

Senior Manager, Teletherapy and Open Sources Board of Radiation & Isotope Technology

Project House, V.N. Purav Marg, Anushakti Nagar, Mumbai 400 094

9869454140 / (022)2556 5535 / 2788 7702

(022)25562161

jacob[at]britatom[dot]gov[dot]in