[99mTc]-Radiopharmaceuticals

[99mTc]-Technetium has become the most widely used radionuclide in diagnostic nuclear medicine due to its physical characteristics of short half-life, low energy of its mono-energetic gamma rays and ease of its incorporation into a wide range of radiopharmaceuticals.

[99mTc]-Technetium is formed from the decay of a parent radionuclide, molybdenum-99, which through this parent-daughter process, can be provided in a  convenient, readily available form such as the recently introduced COLTECH Technetium Generator.

There are other Column Generator products such as geltech generator and  TCM 2 solvent extraction generator which can also be used for preparation of [99mTc]-Technetium labelled radiopharmaceuticals with Technetium Cold Kits supplied by BRIT.

Some of the technetium labelled compounds and their clinical uses are listed:

Radiopharmaceutical BRIT Kit CodeShort formClinical Use

99mTc-Phytate

TCK-16

99m Tc-Phy

Liver imaging

99mTc Sulphur Colloid

TCK-5

99mTcS/C

Liver and spleen imaging

99mTc Mebrofenin

TCK-39

99m Tc-mebro

Hepatobilliary function

99mTc Methylene di Phosphonate

TCK-30

99mTc-MDP

Bone Scan

99mTc Red Blood Cells

TCK-38

99mTc-RBC

Cardiac Function and Blood Pool Scans

99mTc Mibi

TCK-50

99mTc-MIBI

Myocardial Perfusion (Heart Muscle Blood  Flow)

99mTc Diethylene Triamine Penta Acetic Acid

TCK-7

99mTc-DTPA

Renal Function

99mTc Ethylene di cysteine

TCK-43

99mTc-EC

Renal tubular function

99mTc Glucoheptonate

TCK-15

99m Tc-GHA

Kidney imaging

99mTc Ethyl cystienate dimer

TCK-42

99mTc- ECD

Brain Scan and Scans for Infection

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