Annual Report of 2013-2014
Radiation Technologies & Applications
Board of Radiation & Isotope Technology (BRIT) supplies a vast array of high quality radioisotope products for medical and industrial use. BRIT supplies therapeutic and diagnostic radiopharmaceuticals, labelled compounds and nucleotides, radiochemicals, sealed radiation sources and radiation technology equipments including gamma chambers, blood irradiators and radiography exposure devices.
BRIT also offers radiation processing, Isotope applications in industry and radioanalyitcal services to a large number of customers. Besides BRIT signs MoUs for setting up of radiation processing plants in private sector.
Indian Nuclear Society conferred Industrial excellence award upon BRIT recognizing contributions of BRIT for society.
22000 consignments of ready to use radiopharmaceuticals of 131I, 32P, and 153Sm were supplied to Nuclear Medicine Centers. 131I radiopharmaceuticals are most widely used.
BRIT has introduced supply of high dose 131I - NaI therapeutic capsules of 25 - 125 mCi for thyroid cancer treatment. The price of 131I NaI solution have also been reduced substantially. Bulk quantities (500 - 750 mCi) of 131I- NaI solution augments affordability and availability.
The production and supply of injectable product 131I MIBG has increased during the year. MIBG is an important therapeutic and diagnostic product for neurorndocrine cancers.
200 Ci of 99Mo in the form of Sodium molybdate solution for solvent extraction generator and 99Mo-99mTc Gel Generator were supplied. Approximately 375 Ci of 99Mo were also supplied as the new alumina column generator COLTECH.
More than 70000 Technetium cold kits for formulation of 99mTc radiopharmaceuticals (code -TCK: 15 Products) were supplied. Four new 99mTc cold kits TRODAT, HYNICTOC, Tetrofosmin and HSA-NC are now being supplied on more regular basis.
Medical cyclotron facility at Parel continued supplying PET radiopharmaceuticals such as 18F- FDG, 18F-FLT, 18F-NaF and 18F- FMISO to various hospitals equipped with PET technology in and around Mumbai.
Regional Centre Bangalore supplied 72,060 mCi of ready-to-use 99mTc formulations to user retail outlet. Gamma Irradiation of 2580 blood bags was done and 480 consignments were hospitals and 552 cold kits were sold. Radioanalytical laboratory was inaugurated by Director, KMIO Hospital at regional Centre, Bengaluru for residual radionuclide determination and certification in domestic and export commodities.
Regional Centre Delhi supplied ~40,000 mCi of ready to use 99mTc-radiopharmaceuticals for diagnostic nuclear medicine studies in Delhi & NCR Delhi. ~2000 cold kits for labeling 99mTc-99m Radiopharmaceuticals were sold.
The Regional Centre Dibrugarh rendered the RIA and IRMA diagnostic services for the benefit of patients of the entire north-eastern region
At regional Centre Kolkata civil work of DAE Medical Cyclotron is expected to be completed by March 2014 and installation will start by the end of 2014. 68Ge-68Ga generator was evaluated by the optimized method of purification, the average yield of purified 68Ga was around 75%. A new SnO2 based generator is prepared using the isolated 68Ge. Retail outlet sold 150 cold kits to nuclear medicine centres in Kolkata.
Labelled Compounds supplied tritium filled light sources for use in defence applications for illumination of various military gadgets and instruments. 21000 TFS were supplied. Custom synthesis of 14C-radiolabelled Glycosate and 3H-labelled Folic acid were undertaken.
At regional centre Hyderabad a project to develop Real time PCR based M tuberculosis detection kit has got approval under XII plan. The kits for detection of MTb are due for evaluation on clinical samples. Real time PCR kits for determination of Hepatitis B and C, and HIV are under development and detection systems for some cancer markers like EGFR, BCR-ABL are also planned in this project. A new centralized radiopharmacy laboratory for supply of 99mTc as Sodium pertechnetate at Hyderabad has been set up and will commence functioning soon after regulatory clearance.
1300 consignments of 32P labelled nucleotides and ortho-phosphoric acid, 35S amino acids, TAQ Polymerase and PCR Kits and cold kits (TCK products) were supplied.
Radioanalytical laboratory measures and certifies residual radioactivity in various commodities. Around 6000 tests on domestic commodities and 850 tests on water samples (gross alpha, gross beta 228Ra & 228Ra) . During this period, 1556 water samples were analysed from Punjab State for the certification of Uranium content. Radioanalytical laboratory at BRIT Regional Centre, Bangalore has acquired AERB accreditation and has started functioning.
QC analyses of high dose 131I-NaI capsules was performed. Additional shielding Facility for handling and removal of waste during analysis were set up in QC lab. Analysis of imported Technetium cold kits were performed at behest of DCG(I) for regulating the foreign kits from Jubilant Draximage Inc. Canada. A new Solvent extraction generator (99Mo-99mTc) facility was set up at Jonaki, Hyderabad.
Eight cobalt-60 teletherapy sources were supplied to different hospitals with total activity of 58 and 174 RMM using high specific activity imported Co-60.
One unit of Karknidon has been supplied and installed at tata memorial Hospital for cold trial.
Irradiator sources of total of 1630 kCi activity were fabricated and supplied to four radiation processing plants in private sector (NIPRO, Satara, JPCL, Bhiwadi, and AVPP Ltd., Ambernath, MGIP, Srilanka and SARC Delhi).
1000 Ir-192 Radiography Sources ( ~ 43 kCi) and ten Co-60 Radiography Sources (~ 510 Ci ) were fabricated and supplied to various NDT users. Customized radiation sources of Co-60, Cs-137 for Nucleonic Gauges and 25 pencils for were fabricated for Gamma chambers.
RAPPCOF Kota continued excellent work in processing, production and transportation of Cobalt-60. A record 99.59 PBq of Co-60 was processedat Kota in the calendar year 2013. A team also was responsible for source loading at MPGI, Srilanka and SARC Delhi.
ISOMED, an ISO 9001:2008 and ISO 11137:2006 continued radiation sterilization of the medical products and processed 5300 m3 of product (61670 boxes).
Radiation Processing Plant Vashi accredited with ISO-22000:2005 and surveillance audit for ISO-9001:2008 treated 3280 MT of spices and other products registering a growth of about 18.3%.
MoU was signed with M/s Kumaka Industries Ltd., Vadodara for setting up a Radiation Processing plant for treatment of chilled meat, poultry products, sea food etc.
A GC 5000 unit was supplied and installed at Bangladesh Institute of Nuclear Agriculture, Mymensingh.
Two BI 2000 units were supplied and installed at JIPMER, Pondicherry & ISM & SUM hospital, Bhubaneswar.
Two BLC 125 flasks with 250 kCi of Co-60 were exported to Srilanka and old GC 900 unit, BLC 100 & Old GC 5000 units and two empty used BLC 125 flasks were imported from Colombo, Sri Lanka after source loading.
93 radiography exposure devices, 590 ROLI cameras were serviced, 879 imported exposure devices were serviced & inspected and 1376 decayed sources were removed.
A 100 kCi Co-60 based Medical Sterilizer for in-house sterilization of medical products in hospitals and an X-Ray based low dose Irradiator has been designed for Biological studies in cancer, biotechnology, stem cell research, small animal work etc.
120 Ci Co-60 based Radiography Exposure Device has been designed and is under fabrication.
The cold commissioning of install & operate irradiator is completed. The cask has been loaded with 45 kCi of Co-60 at HIRUP Hot Cell.
Isotope Application Services of BRIT in collaboration with National Institute of Hydrology could detect the locations of leak of water from the dam bed in a dam near Chandigarh by using Gold-198 radioisotope.
BPCL pipeline was scanned using gamma pipe scanner containing 5 mCi of Cs-137 developed by BRIT to find the exact location of the stuck pig precisely.
Gamma scanning of various process columns were carried out for a north India refinery using autocolumn scanner. The column was scanned using collimated beam of gamma rays from Co-60 placed in the scanner. Safe transportation of radioactive consignments contyaining different of radioisotope products was carried out by BRIT following AERB and IAEA guidelines.
BRIT website provided regular updates on various programs and activities related to developments in BRIT.
Customer oriented reports were uploaded on website almost on daily basis enhancing co-ordination and communication with the customers.
Fission Molybdenum Project
On completion of this plant BRIT would be able to meet large demand of the most crucial radioisotope 99Mo (n, f). Indigenous production of 99Mo will bring stability in the uncertain market and lower the costs of 99Mo-99mTc generator. It will facilitate the growth of nuclear medicine in India as more patients would benefit with greater availability of high-tech diagnostic procedures.
Radioisotopes and allied products supplied by BRIT
CH 4 Radiation Technologies & Applications
Board of Radiation & Isotope Technology (BRIT) has completed 25 years of its existence as an industrial unit of the Department of Atomic Energy. Significant contributions are made by BRIT to the varied needs of radioisotopes and radiation sources in the country. The radiation and radioisotopes find many applications in the areas related to healthcare agriculture, research and industry. BRIT has a mandate to fulfill this role by regular production and supply of a vast array of high quality radioisotope products and radiation sources.
Chief Executive BRIT receives the INS Industrial Excellence Award from Shri Ratan Tata
In addition to regular production and supply of radiopharmaceuticals BRIT has added many new products, services and developed new production processes facilitating increased production capacity and higher quality products.
126.96.36.199 Ready to use Radiopharmaceuticals
Over 30000 consignments of ready to use radiopharmaceuticals of 131I, 177Lu, 32P and 153Sm containing nearly 1000 Ci were supplied to various Nuclear Medicine Centers for therapeutic and diagnostic purposes.
Hot cell Facility for radiopharmaceutical production
A new facility for production and supply of 131I – NaI high dosage therapeutic capsules for thyroid cancer has started after approval by AERB. Radioiodine therapy has become economical and affordable after process optimization has reduced the prices of ready to use Iodine-131 solutions by 25%. The production capacity and frequency of supply of injectable 131I MIBG has improved considerably. MIBG is an important therapeutic and diagnostic product for treatment of neurorndocrine cancers.
131I radiopharmaceuticals accounted for nearly 600 Ci radioactivity supplied in about 20000 consignments. The revenue generated from these radiopharmaceuticals is of the tune of Rs 10 crores.
Medical cyclotron facility at Parel supplied about 220 consignments of 18F based PET radiopharmaceuticals to nuclear medicine centres with PET scanning facility in Mumbai which accounted for nearly 380 Ci of radioactivity generating a revenue of 6.5 crore.
99mTc is the most widely used radioisotope in nuclear medicine. 99mTc is produced at nuclear medicine centers using various 99Mo-99mTc Generator. BRIT supplies all the three types of 99Mo-99mTc Generators, namely solvent extract generator, gel and column generators.
New AERB approved packing for Coltech Generator
The alumina column generator is the most preferred generator for elution of 99mTc from 99Mo. BRIT had started a facility for production of these generators under the brand name “COLTECH’. Complying with the latest AERB guidelines for transportation of radioactive packages a new package for COLTECH generator was designed, developed and tested. AERB has now permitted BRIT for operation of this production facility at its full capacity.
Over 300 Ci of 99Mo in the form of Sodium molybdate solution has been supplied for solvent extraction generator and for 99Mo-99mTc Gel Generators. Additionally 375 Ci of 99Mo as alumina column generator (New product-COLTECH) has been supplied. BRIT earned a revenue of around Rs. 2.5 crore from these genarotors.
BRIT supplies 15 different Technetium cold kits for labeling and preparing 99mTc-radiopharmaceuticals which are used for diagnosis. During the year 2013-2014.
BRIT has started supplying four new TCK products. TRODAT kit for imaging of somatostatin receptors in tumor imaging, HYNICTOC kit for Dopamine receptors for studying neurological disorders, Tetrofosmin kit for myocardial perfusion imaging and HSA-nanocolloid kit for sentinel node detection.
More than 15000 consignments of cold kits for labeling and preaparation of 99mTc radiopharmaceuticals were supplied to various Nuclear Medicine centers during the year generating a revenue of around 4.5 crores.
RIA procedure for the measurement of insulin in rat serum was developed after modification of human insulin RIA kit. It served as a reliable tool for the measurement of relative rat insulin concentration in studies after more than 200 rat samples were analyzed for various research institutes.
A simple two-step RIA procedure for free T3 as per the guidelines of American Thyroid Association was developed. IRMA kit formulation for human C-peptide was completed. A trial batch of 25 kits were produced for the evaluation of its long term stability.
Around 4500 consignments of radioimmunoassay (RIA) and immunoradiometric assay (IRMA) kits were produced and. The revenue earned by BRIT from the combined RIA and IRMA kits for the year 2013-14 is about Rs. 1.2 crores. RIA Laboratory has received certification for ISO 9001:2008 and ISO 13485:2008 from United Kingdom Accreditation Services (UKAS).
Regional Centre BRIT, Delhi supplied 900 consignments of ready to use Tc-99m Radiopharmaceuticals injections. 2000 technetium cold kits were also supplied to nuclear medicine hospitals in Delhi and NCR Delhi. The revenue earned by RC Delhi was around Rs. 18 lakh.
Regional centre, Bengaluru supplied 300 consignments of ready to use 99mTc formulations. Around 600 TCK cold kits were sold through retail outlet for radiopharmaceuticals. 2500 Blood bags were irradiated using BI 2000. . RC Bengaluru earned a revenue of around 26 lakh. Radioanalytical laboratory was inaugurated by Director, KMIO Hospital at regional Centre, Bengaluru for residual radionuclide determination and certification in domestic and export commodities
At regional Centre Kolkata civil work of DAE Medical Cyclotron is expected to be completed by March 2014. 99mTc produced by 100Mo(p,2n) reaction was separated using Dowex-1 resin and HNO3. The purified 99mTc was found to be suitable for preparation of Tc-radiopharmaceuticals. 68Ge-68Ga generator was evaluated by the optimized method of purification and the average yield of purified 68Ga was around 75 percent. A new SnO2 based generator has been prepared using the isolated 68Ge. Retail outlet for cold kits for radiopharmaceuticals at supplied 200 cold kits to nuclear medicine centres in Kolkata.
The Regional Centre Dibrugarh located at Assam Medical College & Hospital rendered the RIA and IRMA diagnostic services for the benefit of patients of the entire north-eastern region. More than 10,000 patients availed the services offered by this centre for analysis of hormones like T3, T4, TSH, LH, FSH, PRL, beta- HCG, Ferritin and insulin. RC Dibrugarh earned a revenue of Rs. 15 lakh.
Labelled Compounds Programme of BRIT is involved in the synthesis & supply of a variety of 14C, 3H and 35S-labelled products and production of Tritium Filled Self-luminous (TFS) sources for defence applications.
BRIT supplied 42000 TFS sources and was involved custom synthesis and supply of 14C-radiolabelled Glyfosate and 3H-labelled Folic acid. The revenue earned from nearly 1000 consignments containing a total activity of about 1 Ci during the year was about Rs. 22 lakh.
Jonaki, Labelled Biomolecules Laboratory, Regional Centre, BRIT at CCMB Campus is primarily involved in the production and supply of 32P labeled nucleotides and also a few molecular Biology kits and enzymes. RC, Hyderabad has planned a centralized radio pharmacy laboratory for supply of 99mTc as sodium pertechnetate. The laboratory is ready and will be functional for supply of radiopharmaceuticals after regulatory and quality clearance.
Real Time PCR system at Jonaki Hyderabad
Approval for setting up a molecular diagnostic kits project under XII plan for Rs 332 lakh has been sanctioned. The objective of the project is to develop Real time PCR based M tuberculosis detection kit using the patented FRET chemistry developed at Jonaki as a substitute for imported kits. A kit based on real time PCR developed at Jonaki for detection of MTb will shortly go for evaluation on clinical samples. Additional Real time PCR kits for determination of load of viruses like Hepatitis B and C, and HIV are in the process of development. We plan to take up detection system for a few cancer markers like EGFR, BCR-ABL under this plan project.
A total of 1300 consignments were supplied. These comprised mainly 32P nucleotides, 32P orthophosphoric acid, 35S amino acids, LCK Kits, Taq Polymerase and PCR Product, radiopharmaceuticals cold kits (TCK products). The revenue earned was about Rs. 200 Lakh.
Radioanalytical laboratory routinely carries out the measurement and certification of residual radioactivity in various commodities such as food items for human & animal consumption, water samples, environmental samples, steel and other miscellaneous items.
Radioanalytical Laboratory at Bengaluru inaugurated by Director KMIO
During the 2013-14 RAL has carried out more than 8000 tests on export/domestic commodities and 1100 tests on water samples (gross alpha, gross beta 228Ra & 228Ra). During the period, nearly 3000 water samples received from Punjab State were analysed for the certification of uranium content. 5 steel surveys were conducted for certification of surface radiation dose and 80 food samples imported from Japan were also analysed and certified.
Radioanalytical laboratory at BRIT Regional Centre, Bangalore obtained AERB accreditation and has started functioning.
QC analyses of 131I-NaI capsules of high denomination was performed. Additional shielding Facility for handling and removal of waste during analysis of 50-100 mCi capsules were set up in QC lab.
A new Solvent extraction generator (99Mo-99mTc) facility was set up at Jonaki, Hyderabad and the staff was trained for active operation and QC analysis. Studies on Extension of shelf life of TCK 42 is completed. The kit was found to be stable for 12 months from the date of production.
Analysis of imported cold kits for preparation of 99mTc-radiopharmacuticals was taken up as a requirement from the DCG(I) for regulating the kits being supplied by foreign companies in India. A total of 12 kits including 3 batches DTPA kits, MDP kit for and sestamibi kit and MAA kit manufactured by a Canada based were analyzed for compliance with approved monographs.
Co-60 Teletherapy Sources : 7 teletherapy sources were supplied to different hospital with total activity of about 70 kCi ranging from 60 and 180 RMM and another 5 sources were loaded in the flask for transportation to hospitals. Ten decayed sources were unloaded from the teletherapy units and stored for fabrication of irradiator source.
Brachythearpy Applications : 100 mCi of ( Ir-192 + Pt Wire) and 500 mCi of Cs-137 were supplied for brachytherapy applications.
The various engineering products and services offered by BRIT included a supply of more than 2000 kCi of radioactivity in various forms and uses. The combined revenue for the engineering products and radiation processing services was close to about Rs 40 crores.
Industrial Irradiator Sources: Irradiator sources with total activity of around 2000 kCi were supplied in eight consignments to various raditation processing plants in the country. A record single consignment of 882 kCi supplied to NIPRO, Satara. Sources supplied to MGIP Srilanka were also successfully loaded in the irradiator at Srilanka. The total revenue earned from Cobalt-60 Irradiator sources during the year was about Rs. 17 Crores.
Radiography Sources : Nearly 1400 radiography consignments of Ir-192 and Cobalt-60 sources with total activity of approx. 60 kCi were supplied to various radiography camera customers in the country. The revenue earned from radiography source replenishment and other services offered by BRIT during the year was approximately Rs. 11 crores.
Custom Made Sources: Custom Made Radiation Sources for Nucleonic Gauges and other uses were made with the two isotopes Co-60 and Cs-137.
Co-60 : 2 sources with activity of 185 mCi mCi
Cs-137 : 20 sources with total activity of 720 mCi
A total of 5 Ci of radioactivity was supplied for reference and custom made sources during the year 2013-14 for a revenue of Rs. 40 lakh.
Gamma Chambers : One Gamma Chamber (GC 5000 unit) was loaded with 14 kCi of Co-60 radioactivity in 25 source pencils for the GC 5000 unit. Decayed source from one GC-900 were removed and stored in the storage flask. 510 Ci in 10 nos. of sources.
Radiometry of Install and irradiate operator was done and it was decided to fabricate another set of pencils for further radiometry with 50 kCi of Cobalt-60. Refurbishment of one hot cell window was undertaken to improve the transmission efficiency.
A meeting was held with US representative for repatriation of radiation sources of US origin supplied to India for sending back to USA. Cs-137 source used for oil logging at ONGC were recovered. The source rack and related equipments were inspected at SYMEC engineers, Navi Mumbai before shipment to Ethiopia..
A record 2 MCi of Cobalt-60 was processed at Regional Centre RAPPCOFF, Kota during the period. Safe handling, transportation of adjuster rods from various reactors and processing of Cobalt-60 at RAPPCOF and subsequent transportation for fabrication of irradiator sources to Mumbai and the necessary decontamination of the facility were performed. Approximately 2.36 MCi of Cobalt-60 activity was transported in 17 consignments. Mobile hot cell was used to remove 16 numbers of Co-60 pencils as a test case. Decayed Cs-137 sources were removed and loaded in the transport flask at 4 customer centres. The centre was also involved in the source loading operations at Sri Lanka and SARC Delhi. Customized W-91 pencils for install and operate irradiator were prepared.
ISOMED facility, engaged in contract gamma radiation processing services for terminal sterilization of the medical products has processed 7400 m3 of product (approx 90000 boxes of Medical products) during the financial year 2013-2014 earning a revenue of ~ Rs. 300 lakhs.
The average plant utilization factor was around 95%. The certifications issued to Isomed facility complying to the requirements of various International Standards viz. ISO 9001:2008, ISO 13485:2003, ISO 11137:2006 (part1), ISO 22000:2005, OHSAS 18001:2007 facilitated the desired cutting edge to the facility in the radiation sterilization sector in the country.
Radiation Processing Plant, Vashi has treated approx 42 MT of spices and other products during the financial year 2013-2014 registering a growth of about 18 %. It has earned a revenue of Rs. 350 lakhs which is about 30 % more than that in the previous year.
New products like lead impregnated rubber sheets and Corncob for animal bedding were added for commercial processing. The facility re-qualified the certification audit for compliance to ISO-22000:2005 (Food Safety Management Systems) and surveillance audit for ISO-9001:2008 (Quality Management Systems) thus proving its excellence in meeting customer requirements.
Motivated by the successful commercial operation of private sector Radiation Processing facilities in the country, M/s Kumaka Industries Ltd., Vadodara has signed an MoU with BRIT for setting up a radiation processing facility. The facility will come up at Sanand II, Gujarat for treatment of spices, chilled meat, poultry products, sea food etc.
MoU signed with M/s Kumaka Industries Ltd., Vadodara for setting up a RP Plant at Sanand in Gujarat.
188.8.131.52 EB Processing
Electron Beam commercial processing services were continued at ILU-6 facility at Vashi.
8 nos. of Gamma Chamber - 900 units, 1 no. of PANBIT facility & 1 no. of Gamma Shine 1000 units were decommissioned for the disposal of their decayed cobalt-60 source from different Institutions
Two Blood Irradiator 2000 units (BI 2000) and one Low dose Irradiator were supplied and installed at JIPMER, Pondicherry & ISM & SUM hospital, Bhubaneswar with nearly 2000 Ci of Cobalt-60 radioactivity earning a revenue of around Rs. 80 lakh to BRIT for the year 2013-14.
125 flask for exporting Cobalt-60 to Sri Lanka
A 3 MCi multipurpose Irradiator has been set up at Colombo, Sri Lanka jointly with a private company and has been commissioned. BRIT had also carried out repatriation of 3 gamma chambers which were earlier exported to Sri Lanka from Colombo and Kandy on chargeable basis.
BRIT supplied 90 new radiography exposure devices earning a revenue of around Rs. 3.3 crore. Besides these under radiography services offered by BRIT around 500 ROLI cameras were serviced, 900 imported exposure devices were serviced & inspected and 1400 decayed sources were removed earning an additional revenue of Rs. 70 lakh.
A Medical Sterilizer cat II batch irradiator with a source strength of 100 kCi of Co-60 for sterilization of medical product for in-house application of hospitals has been successfully designed and a scale down model has been fabricated. X-Ray based Irradiator
A X-Ray based low dose Irradiator has been designed for Biological studies in cancer, biotechnology, stem cell research, small animal work etc.
A 120 Ci Co-60 based Radiography Exposure Device for industrial application has been designed and it is under fabrication.
The cold commissioning of install & operate irradiator is completed. Now the cask has been loaded with 45 kCi of Co-60 at HIRUP Hot Cell.
Isotope Application Services Group of BRIT offered its valuable services
The exact location of a stuck ‘pig’ in BPCL pipeline was scanned using gamma pipe scanner containing 5 mCi of Cs-137 developed by Isotope Application Services of BRIT.
Gamma Pipe scanning at BPCL
The method saved downtime of the pipe by number of days saving several crores of rupees due to transportation by alternate means.
Gamma scanning of various process columns were carried out for a north India refinery using auto-column scanner that was scanned using collimated beam of gamma rays from Co-60 in the scanner.
Gamma scanning of process columns for a North India refinery
Diesel produced from one of the crude distillation unit of a refinery in north India was blackish in colour resulting in the rejection by their QA deptt. The column was scanned using collimated beam of gamma rays from Co-60 placed in and it was found that one of the packed bed in diesel section has heavy coke depositions and asphaltenes. After shutdown, the packed bed was replaced which reinstated the quality of diesel.
In collaboration with National Institute of Hydrology, Roorkee the Isotope Application Services group of BRIT detected the locations of leak of water from the dam bed in a dam near Chandigarh by using a radioisotope of Gold (198Au). Water accumulated during rainy season used to get emptied out by the end of January. It was suspected to be due to leaking from the dam bed. (NIH) roughly estimated the suspected zones. NIH had requested BRIT to identify the exact locations of the leaks.
Location of underwater leak from the dam bed using gold radioisotope
Isotope Application Services group of BRIT earned a revenue of Rs. 1.6 crores during the year 2013-2014.
4.14. Supporting Services
Customer Support Programme provides various kind of support for the regular and uninterrupted supply of radioisotopes & allied products and radiation technology equipment to about 2000 user institutions in the healthcare, industrial, research and agricultural sector.
The transportation of nearly about 100,000 consignments of radioisotope and allied products, majority of them by air was carried out in a safe manner. Major transportation activities carried out during the year includes movement of several kilocuries of radioactive sources from RAPPCOF, Kota to Mumbai, and transportation of industrial irradiator sources from Mumbai to different industrial radiation processing plants in the private sector. Safe transportation of our various radioisotope product consignments to nuclear medicine centres, hospitals and research institutions was pursued on a routine basis. Suppply, transportation and installation of radiation technology equipments were also undertaken.
BRIT achieved a total sales turnover of Rs. 80.02 crores during the year 2013-2014.
The projects under XIth plan viz. Integrated Facility for Radiation Technology, Industrial Irradiator Development Project and GMP and GLP compliant labeled compounds laboratory have been completed.
X Plan Projects
Project: DAE Medical Cyclotron Project: Pharmaceuticals Facility
A medical cyclotron facility is being installed at VECC, DAE, and Kolkata for the production of PET and SPECT radioisotopes to be used for diagnostic and therapeutic purposes.
Progress: Civil work is expected to be completed in 2014.
XI Plan Projects
1. Project: Indigenous HDR Brachytherapy Equipment (IHDR)
Estimated cost: Rs. 800 lakhs
a) Establishing the complete process and facilities for fabrication of Ir-192 HDR
b) sources for regular production.
c) Development of indigenous, remote operated high dose rate (HDR) brachytherapy equipment including necessary treatment.
Brachytherapy unit supplied to Tata Memorial Hospital
Seven HDR Brachytherapy units have already been received for which the development was completed earlier. One unit has been installed at Tata Memorial Hospital, Parel for trials.
2. Project: Setting up of facility for production of medical grade Fission Molybdenum
Estimated Cost Rs. 128 crore (To be revised)
· State-of-the Art GMP compliant facility capable of producing 300Ci (6 day pre-calibrated) /week 99Mo, utilizing LEU targets.
· Supply Fully indigenous column generators to various diagnostic centres and hospitals in the country.
After the site clearance by AERB, the design documents for the building have been submitted to AERB. As per requirements of security and safety authorities, the work of construction of new RCC boundary wall for the complex, new security watch tower is over and installation of new security and surveillance equipment is ongoing. The work on construction of laboratory building is nearing completion. The procurement of the production plant, on turnkey basis, is progressing. The cost of project has increased beyond the sanctioned cost, mainly because of high end, strategic technology cost component. The revised project report and revised demands have been submitted to DAE and AEC for sanction.
Civil construction for Fission Molybdenum Project for 99Mo (n, f) is under progress.